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Apexion Health SS-31 treatment vial
LONGEVITYMITOCHONDRIAL

MONTHLY SUPPLY · INJECTION

SS-31

TREATMENT

Mitochondria-targeted tetrapeptide that protects cardiolipin from oxidative damage, restoring cellular energy production and reducing free radical burden.

SUPPORT

SS-31 (elamipretide) is a mitochondria-targeted peptide that binds to cardiolipin, a phospholipid crucial for mitochondrial function. By protecting cardiolipin from oxidative damage, SS-31 helps maintain the efficiency of the electron transport chain and reduces reactive oxygen species production within mitochondria.

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Lab-Tested · Physician-Supervised · Discreet Delivery

Apexion Health — LONGEVITY

PROTECT YOUR MITOCHONDRIA. PRESERVE YOUR ENERGY.

Cardiolipin is a unique phospholipid found almost exclusively in the inner mitochondrial membrane where it plays a critical role in organizing the proteins involved in energy production. As we age, cardiolipin becomes increasingly susceptible to oxidative damage, which can impair mitochondrial function and reduce cellular energy output. SS-31 directly addresses this mechanism of age-related decline by binding to and stabilizing cardiolipin, thereby preserving mitochondrial efficiency and reducing oxidative stress within the organelle.

Clinical Benefits

SS-31 SUPPORTS YOUR HEALTH AT THE CELLULAR LEVEL

  1. 01.

    BINDS TO AND STABILIZES CARDIOLIPIN IN MITOCHONDRIA

  2. 02.

    PROTECTS AGAINST OXIDATIVE DAMAGE TO MITOCHONDRIAL MEMBRANES

  3. 03.

    SUPPORTS ELECTRON TRANSPORT CHAIN EFFICIENCY

  4. 04.

    REDUCES MITOCHONDRIAL REACTIVE OXYGEN SPECIES PRODUCTION

  5. 05.

    SUPPORTS CELLULAR ENERGY PRODUCTION AND VITALITY

  6. 06.

    PHYSICIAN-SUPERVISED MITOCHONDRIAL SUPPORT PROTOCOL

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Clinical Evidence

How It Works in the Body

01 — Dose & Efficacy

Mitochondrial Protection Profile

Cardiolipin Stabilization Binds & protects inner membrane80%
ATP Preservation Maintained under oxidative stress60%
ROS Reduction Decreased electron leakage55%

Szeto, AAPS J 2006; Birk et al., J Am Soc Nephrol 2013

02 — Hormone Panel

Mitochondrial Function Markers

MarkerWithoutWith Treatment
Cardiolipin PeroxidationRel.
Elevated (disease/aging)
Significantly reducedProtected
Complex IV Activity%
Declined under stress
Preserved activityMaintained
Mitochondrial ROS%
Baseline (high)
↓ 30–50% in models−30–50%
ATP/ADP RatioRatio
Decreased
Restored toward normalImproved

Cardiolipin is the Achilles heel of aging mitochondria

Cardiolipin makes up ~20% of the inner mitochondrial membrane and is essential for cristae structure and ETC supercomplex assembly. It is uniquely susceptible to peroxidation. SS-31's cardiolipin-binding mechanism directly addresses this vulnerability.

Szeto, AAPS J 2006; Birk et al., JASN 2013; Szeto & Birk, Ann Rev Pharmacol 2014

03 — Protocol

SS-31 Mitochondrial Support Protocol

BaselinePre-treatment
  • ›Energy & fatigue inventory
  • ›Exercise tolerance assessment
  • ›Metabolic panel & antioxidant markers
Loading PhaseWeeks 1–8
  • ›SC injection per protocol (typically daily)
  • ›Energy & recovery tracking weekly
  • ›Tolerability assessment
MaintenanceMonth 3+
  • ›Reassess energy & function at 3 months
  • ›Continue or cycle per protocol
  • ›Metabolic markers q3 months

Targets the fundamental aging mechanism in mitochondria

Unlike general antioxidants, SS-31 concentrates at the inner mitochondrial membrane where ROS production is highest. Most clinical evidence from heart failure, mitochondrial myopathy, and renal ischemia-reperfusion models.

All protocols physician-supervised and adjusted per individual labs.